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Clomethiazole

CAS No. 533-45-9

Clomethiazole( Chlormethiazole | 5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | Distraneurin )

Catalog No. M24511 CAS No. 533-45-9

Clomethiazole is an orally active GABAA?agonist and it is an anticonvulsant agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Clomethiazole
  • Note
    Research use only, not for human use.
  • Brief Description
    Clomethiazole is an orally active GABAA?agonist and it is an anticonvulsant agent.
  • Description
    Clomethiazole is an orally active GABAA?agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Chlormethiazole | 5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | Distraneurin
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Other Targets
  • Recptor
    GABAA|CYP2A6|CYP2E1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    533-45-9
  • Formula Weight
    161.65
  • Molecular Formula
    C6H8ClNS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 240 mg/mL?(1484.69 mM;?Need ultrasonic)
  • SMILES
    Cc1c(CCCl)scn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nelson RM, et al.Electrophysiological actions of gamma-aminobutyric acid and clomethiazole on recombinant GABA(A) receptors.Eur J Pharmacol. 2002 Oct 11;452(3):255-62.
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