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Clofarabine
CAS No. 123318-82-1
Clofarabine ( Clolar; Evoltra )
Catalog No. M10922 CAS No. 123318-82-1
Clofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 32 | In Stock |
|
| 10MG | 49 | In Stock |
|
| 25MG | 78 | In Stock |
|
| 50MG | 122 | In Stock |
|
| 100MG | 158 | In Stock |
|
| 200MG | 204 | In Stock |
|
| 500MG | 341 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameClofarabine
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NoteResearch use only, not for human use.
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Brief DescriptionClofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
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DescriptionClofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
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SynonymsClolar; Evoltra
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorRR
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number123318-82-1
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Formula Weight303.68
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Molecular FormulaC10H11ClFN5O3
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Purity>98%(HPLC)
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SolubilityDMSO: 60 mg/mL (197.57 mM)
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SMILESO[C@H]1[C@H](CO)O[C@@H](N2C=NC3=C(N)N=C(Cl)N=C23)[C@@H]1F
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Chemical Name(2S,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bonate PL, et al. Nat Rev Drug Discov, 2006, 5(10), 855-863.
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