Cladribine ( Biodribin; 2-Chlorodeoxyadenosine; Jk 6251; Leustatin; NSC 105014; RWJ 26251 )

Catalog No. M14455 CAS No. 4291-63-8

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Product Name

Cladribine
Note

Research use only, not for human use.
Brief Description

Cladribine is an adenosine deaminase inhibitor used to treat hairy cell leukemia and multiple sclerosis.
Description

Cladribine is an adenosine deaminase inhibitor used to treat hairy cell leukemia and multiple sclerosis.
Synonyms

Biodribin; 2-Chlorodeoxyadenosine; Jk 6251; Leustatin; NSC 105014; RWJ 26251
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

Adenosine deaminase (MM1.S cells); Adenosine deaminase (RPMI8226 cells); Adenosine deaminase (U266 cells)
Research Area

Cancer
Indication

——

CAS Number

4291-63-8
Formula Weight

285.69
Molecular Formula

C10H12ClN5O3
Purity

>98%(HPLC)
Solubility

DMSO: 57 mg/mL (199.51 mM)
SMILES

O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(N)N=C(Cl)N=C23)C1
Chemical Name

(2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

1.Kopadze T, et al. Eur J Neurol. 2009, 16(3), 409-412.

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