Cirsimaritin

CAS No. 6601-62-3

Cirsimaritin ( —— )

Catalog No. M29601 CAS No. 6601-62-3

Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 189 Get Quote
10MG 267 Get Quote
25MG 471 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Cirsimaritin
  • Note
    Research use only, not for human use.
  • Brief Description
    Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.
  • Description
    Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.(In Vitro):Cirsimaritin inhibits the growth of tumor cells and induced mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt . Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner .(In Vivo):Cirsimaritin significantly reduces anxiety in mice. The high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6601-62-3
  • Formula Weight
    314.3
  • Molecular Formula
    C17H14O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • PACAP (1-38), human,...

    PACAP (1-38), human, ovine, rat TFA is a neuropeptide with 38 amino acid residues. PACAP (1-38) binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively. IC50: 4 nM (PACAP type I receptor), 2 nM (PACAP type II receptor VIP1), and 1 nM (PACAP type II receptor VIP2).

  • Djenkolic Acid

    Djenkolic Acid is a naturally occurring sulfur-containing amino acid extracted from djenkol beans(Archidendron pauciflorum), which is native to Southeast Asia.

  • Calmodulin-Dependent...

    Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).