Cholestenone
CAS No. 601-57-0
Cholestenone ( (+)-4-Cholesten-3-one )
Catalog No. M19974 CAS No. 601-57-0
4-Cholesten-3-one is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCholestenone
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NoteResearch use only not for human use.
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Brief Description4-Cholesten-3-one is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals.
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Description4-Cholesten-3-one is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals.
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Synonyms(+)-4-Cholesten-3-one
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number601-57-0
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Formula Weight384.64
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Molecular FormulaC27H44O
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Purity>98% (HPLC)
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SolubilityEthanol: 2 mg/mL
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SMILESCC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rosenheim O et al. The mechanism of coprosterol formation in vivo: 1. Cholestenone as an intermediate. Biochem J. 1943 Oct;37(4):513-4.
molnova catalog
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OD1
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.