Chloroxylenol( —— )

Catalog No. M16385 CAS No. 88-04-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Chloroxylenol
Note

Research use only, not for human use.
Brief Description

Chloroxylenol (4-chloro-3,5-dimethylphenol) is a broad spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.
Description

Chloroxylenol (4-chloro-3,5-dimethylphenol) is a broad spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus. It is used in hospitals and households for disinfection and sanitation.
In Vitro

RT-PCR Cell Line:HCT116 and SW480 CRC cells Concentration:62.5-250 μM Incubation Time:24 h Result:Decreased mRNA level Axin2, Survivin and LGR5, which indicates the antagonistic effect of Chloroxylenol on the Wnt/β-catenin signaling.
In Vivo

Animal Model:MC38 cell xenograft modelDosage:5 mg/kg Administration:i.p., on days 0, 2, 4, 6, 8 and 10 Result:Reduced umor volume and weight.Reduced tumor cell density (H&E).Inhibited the expression of cancer stemness marker LGR5 in the tumor tissue, as well as the expression levels of LGR5 and SOX2.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Infection
Indication

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1. Xu L, Wang J. Environ Eng Sci. 2013 Jun;30(6):294-30

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