Cepharanthine ( O-Methylcepharanoline; NSC 623442 )

Catalog No. M14609 CAS No. 481-49-2

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Product Name

Cepharanthine
Note

Research use only, not for human use.
Brief Description

Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.
Description

Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.
Synonyms

O-Methylcepharanoline; NSC 623442
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Cancer
Indication

——

CAS Number

481-49-2
Formula Weight

606.73
Molecular Formula

C37H38N2O6
Purity

>98%(HPLC)
Solubility

DMSO: 100 mg/mL (164.82 mM)
SMILES

COC1=CC2=C3C=C1OC4=C(OCO5)C5=CC6=C4[C@@](CC7=CC=C(OC(C(OC)=C8)=CC=C8C[C@@]3([H])N(C)CC2)C=C7)([H])N(C)CC6
Chemical Name

(15S,31R)-36,53-dimethoxy-16,32-dimethyl-15,16,17,18,31,32,33,34-octahydro-2,6-dioxa-1(4,5)-[1,3]dioxolo[4,5-g]isoquinolina-3(7,1)-isoquinolina-5,7(1,4)-dibenzenacyclooctaphane

1.Huang H, et al. Inflammation. 2014 Feb;37(1):235-46.

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