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Cefoperazone

CAS No. 62893-19-0

Cefoperazone ( Cefobid; Cefozon; T1551; T 1551 )

Catalog No. M18925 CAS No. 62893-19-0

Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
200MG 27 In Stock
500MG 39 In Stock
1G 52 In Stock
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Biological Information

  • Product Name
    Cefoperazone
  • Note
    Research use only, not for human use.
  • Brief Description
    Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
  • Description
    Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. It can inhibit rMrp2-mediated [3H]E217βG uptake (IC50: 199 μM).
  • Synonyms
    Cefobid; Cefozon; T1551; T 1551
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    62893-19-0
  • Formula Weight
    645.67
  • Molecular Formula
    C25H27N9O8S2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 100 mg/mL 154.88 mM H2O : < 0.1 mg/mL
  • SMILES
    [H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=O
  • Chemical Name
    (6R,7R)-7-((R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kato, Y., et al., Involvement of multidrug resistance-associated protein 2 (Abcc2) in molecular weight-dependent biliary excretion of beta-lactam antibiotics. Drug Metab Dispos, 2008. 36(6): p. 1088-96.
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