Cbz-NH-PEG2-CH2COOH( —— )

Catalog No. M26936 CAS No. 165454-06-8

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Cbz-NH-PEG2-CH2COOH
Note

Research use only, not for human use.
Brief Description

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Apoptosis| PDK4
Research Area

——
Indication

——

Chemical Information

CAS Number

165454-06-8
Formula Weight

297.307
Molecular Formula

C14H19NO6
Purity

>98% (HPLC)
Solubility

——
SMILES

OC(=O)COCCOCCNC(=O)OCc1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lee D, et al. Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. J Med Chem. 2019 Jan 24;62(2):575-588.

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