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Carbobenzoxyproline
CAS No. 1148-11-4
Carbobenzoxyproline( Benzyloxycarbonylproline,Carbobenzoxy-S-proline )
Catalog No. M22867 CAS No. 1148-11-4
Carbobenzoxyproline is a prolidase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 35 | In Stock |
|
| 1G | 46 | In Stock |
|
Biological Information
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Product NameCarbobenzoxyproline
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NoteResearch use only, not for human use.
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Brief DescriptionCarbobenzoxyproline is a prolidase inhibitor.
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DescriptionCarbobenzoxyproline is a prolidase inhibitor.
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In VitroCarbobenzoxyproline (6 mM; 0-10 d; pH=6.0) causes mitochondrial depolarization and increases cellular death by 33% as reported for long-term culture of fibroblasts from prolidase deficiency (PD) patients. Carbobenzoxyproline (0, 1, 3, 6 mM; 1 min; pH=6.0) results fibroblasts prolidase (FBP) hydrolysis, shows linear competitive inhibition.
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In VivoCarbobenzoxyproline (60 mg/kg; injection; once daily; 3 weeks) serves as in vivo inhibitor of erythrocytes prolidase in mice model. Animal Model:C57Bl/6J mice (4-week-old)Dosage:60 mg/kg Administration:Injection; once daily for 3 weeks Result:Resulted significant reduction of erythrocytes prolidase activity.
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SynonymsBenzyloxycarbonylproline,Carbobenzoxy-S-proline
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PathwayOthers
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TargetOther Targets
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Recptorprolidase
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Research Area——
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Indication——
Chemical Information
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CAS Number1148-11-4
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Formula Weight249.26
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Molecular FormulaC13H15NO4
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble
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SMILESC1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Arkadiusz, Surazynski, and, et al. Prolidase-dependent regulation of TGF c and TGF β receptor expressions in human skin fibroblasts[J]. European Journal of Pharmacology, 2010, 649(1-3):115-119.
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