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Carbobenzoxyphenylalanine
CAS No. 1161-13-3
Carbobenzoxyphenylalanine ( Carbobenzoxy-L-phenylalanine,NSC 402059,NSC-402059 )
Catalog No. M22870 CAS No. 1161-13-3
Carbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 26 | In Stock |
|
Biological Information
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Product NameCarbobenzoxyphenylalanine
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NoteResearch use only, not for human use.
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Brief DescriptionCarbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?
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DescriptionCarbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?The inhibitions of chromatin-bound protease in rat liver by these compounds are irreversible.?On the other hand, carbobenzoxyphenylalanine and p-nitrophenyl acetate were shown to be reversible inhibitors of rat liver chromatin-bound protease.
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SynonymsCarbobenzoxy-L-phenylalanine,NSC 402059,NSC-402059
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PathwayOthers
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TargetOther Targets
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Recptorthermolysin
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Research Area——
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Indication——
Chemical Information
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CAS Number1161-13-3
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Formula Weight299.32
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Molecular FormulaC17H17NO4
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble
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SMILESC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Carter DB, Chae CB. Chromatin-bound protease: degradation of chromosomal proteins under chromatin dissociation conditions. Biochemistry. 1976 Jan 13;15(1):180-5. PubMed PMID: 2280.
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