Carbobenzoxyphenylalanine

CAS No. 1161-13-3

Carbobenzoxyphenylalanine( Carbobenzoxy-L-phenylalanine,NSC 402059,NSC-402059 )

Catalog No. M22870 CAS No. 1161-13-3

Carbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1G 26 In Stock

Biological Information

  • Product Name
    Carbobenzoxyphenylalanine
  • Note
    Research use only, not for human use.
  • Brief Description
    Carbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?
  • Description
    Carbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?The inhibitions of chromatin-bound protease in rat liver by these compounds are irreversible.?On the other hand, carbobenzoxyphenylalanine and p-nitrophenyl acetate were shown to be reversible inhibitors of rat liver chromatin-bound protease.
  • In Vitro
    Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances.
  • In Vivo
    ——
  • Synonyms
    Carbobenzoxy-L-phenylalanine,NSC 402059,NSC-402059
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    thermolysin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1161-13-3
  • Formula Weight
    299.32
  • Molecular Formula
    C17H17NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    C1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Carter DB, Chae CB. Chromatin-bound protease: degradation of chromosomal proteins under chromatin dissociation conditions. Biochemistry. 1976 Jan 13;15(1):180-5. PubMed PMID: 2280.
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