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Carbendazim
CAS No. 10605-21-7
Carbendazim( Mercarzole | Carbendazole. Code name: FB462 )
Catalog No. M10269 CAS No. 10605-21-7
Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 200MG | 32 | Get Quote |
|
| 500MG | 56 | Get Quote |
|
| 1G | 80 | Get Quote |
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Biological Information
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Product NameCarbendazim
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NoteResearch use only, not for human use.
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Brief DescriptionCarbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities.
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DescriptionCarbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities.(In Vitro):Carbendazim (4-60 μM; 24 hours) has no effects on viability of HeLa cells in a CCK-8 assay.(In Vivo):Carbendazim (oral gavage; 100 and 500 mg/kg; once daily in diet; 28 days) induces hepatic lipid metabolism disorder, it results in a significant increase of hepatic lipid accumulation and triglyceride (TG) levels in mice.
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In Vitro——
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In VivoAnimal Model:6-week-old male ICR miceDosage:100 and 500 mg/kg Administration:Oral gavage; 100 and 500 mg/kg; once daily in diet; 28 days Result:Increased the relative mRNA levels of some key genes related to lipogenesis and TG synthesis.Up-regulated mRNA levels of IL-1b and IL-6 in the liver in mice.Increased the serum concentrations of 2 proinflammatory cytokines IL-1b and IL-6 at 500 mg/kg. However, in the fat tissues, onlyIL-1b in the CBZ-500-treated group increased significantly as compared with the control group.
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SynonymsMercarzole | Carbendazole. Code name: FB462
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number10605-21-7
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Formula Weight191.19
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Molecular FormulaC9H9N3O2
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=C(OC)NC1=NC2=CC=CC=C2N1
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Chemical Namemethyl 1H-benzo[d]imidazol-2-ylcarbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Goitrin
Goitrin is a potent antithyroid compound found naturally in crucifers. Goitrin is responsible for the induction of glutathione S-transferases.
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Alpinumisoflavone
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is endowed with estrogenic properties accounting, at least in part, for E. lysistemon effects.
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2',5'-Dideoxyadenosi...
2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).2',5'-Dideoxyadenosine (20-150 mM), like adenosine, dependently and reversibly inhibits the positive inotropic and chronotropic effect of beta-adrenergic stimulation with isoproterenol (8-54 pmol) up to 70% and 50%, respectively.
