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Cabotegravir
CAS No. 1051375-10-0
Cabotegravir( S/GSK1265744 | GSK 744 | Cabotegravir )
Catalog No. M17126 CAS No. 1051375-10-0
Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 41 | In Stock |
|
| 25MG | 80 | In Stock |
|
| 50MG | 142 | In Stock |
|
| 100MG | 178 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCabotegravir
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NoteResearch use only, not for human use.
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Brief DescriptionCabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).
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DescriptionCabotegravir, also known as S/GSK1265744 or GSK744, is potent HIV integrase inhibitor under development for the treatment of HIV infection. Cabotegravir has a carbamoyl pyridone structure similar to dolutegravir.
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In VitroCell Viability Assay Cell Line:MT-4 cells Concentration:0-32 nM Incubation Time:4 or 5 days Result:Showed antiviral activity with an EC50 of 1.3 nM.
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In Vivo——
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SynonymsS/GSK1265744 | GSK 744 | Cabotegravir
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PathwayOthers
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TargetOther Targets
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RecptorHIV integrase
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number1051375-10-0
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Formula Weight405.35
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Molecular FormulaC19H17F2N3O5
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Purity>98% (HPLC)
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SolubilityDMSO : 12.67 mg/mL 31.26 mM;
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SMILESC[C@H]1CO[C@H]2N1C(=O)c1c(c(=O)c(cn1C2)C(=O)NCc1c(cc(cc1)F)F)O
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Chemical Name(3S,11aR)-N-(2,4-difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yoshinaga T, et al. Antimicrob Agents ChemOthers. 2015, 59(1), 397-406.
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