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CZC24832
CAS No. 1159824-67-5
CZC24832 ( CZC24832; CZC-24832; CZC 24832 )
Catalog No. M10554 CAS No. 1159824-67-5
CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 55 | In Stock |
|
| 5MG | 88 | In Stock |
|
| 10MG | 133 | In Stock |
|
| 25MG | 227 | In Stock |
|
| 50MG | 338 | In Stock |
|
| 100MG | 498 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCZC24832
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NoteResearch use only, not for human use.
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Brief DescriptionCZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
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DescriptionCZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins.
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SynonymsCZC24832; CZC-24832; CZC 24832
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3Kβ; PI3Kγ; PI3Kδ
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number1159824-67-5
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Formula Weight364.40
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Molecular FormulaC15H17FN6O2S
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Purity>98%(HPLC)
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SolubilityDMSO: 5 mg/mL warmed (13.72 mM)
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SMILESO=S(C1=CC(C2=CN3C(C(F)=C2)=NC(N)=N3)=CN=C1)(NC(C)(C)C)=O
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Chemical Name5-(2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)pyridine-3-sulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bergamini G, et al. Nat Chem Biol, 2012, 8(6), 576-582.
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