
CYM50260
CAS No. 1355026-60-6
CYM50260( —— )
Catalog No. M23514 CAS No. 1355026-60-6
CYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 323 | In Stock |
![]() ![]() |
10MG | 483 | In Stock |
![]() ![]() |
25MG | 781 | In Stock |
![]() ![]() |
50MG | 1071 | In Stock |
![]() ![]() |
100MG | 1431 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameCYM50260
-
NoteResearch use only, not for human use.
-
Brief DescriptionCYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM).
-
DescriptionCYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM). CYM50260 shows no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.
-
In VitroCYM50260 (Compound 22aa) is a synthetic S1P4-R agonist. CYM50260 is found 3.5-fold more potent than the hit compound (HTS-hit).CYM50260 suppresses the collagen-stimulated platelet aggregation, PDGF-AB secretion and sCD40L release. CYM50260 reduces the release of phosphorylated-HSP27 by collagen as well as the phosphorylation of HSP27.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorS1P4-R
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1355026-60-6
-
Formula Weight350.6
-
Molecular FormulaC14H11Cl3FNO2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (356.53 mM)
-
SMILESFCC1=CC=C(OCCOC2=CC=C(Cl)C=C2Cl)C(Cl)=N1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P?-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22(1):537-42.
molnova catalog



related products
-
10-O-trans-p-Feruloy...
The herbs of Hedyotis diffusa Willd.
-
Endothelin 3 (Rat,Hu...
Endothelin-3, human, mouse, rabbit, rat TFA is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
-
naphthalene-1,3,6,8-...
The pentaketide 1,3,6,8-tetrahydroxynaphthalene (T4HN) is a key precursor of 1,8-dihydroxynaphthalene-melanin.