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CY-09
CAS No. 1073612-91-5
CY-09( NLRP3 inhibitor CY-09 )
Catalog No. M10304 CAS No. 1073612-91-5
CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 61 | In Stock |
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| 10MG | 106 | In Stock |
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| 25MG | 222 | In Stock |
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| 50MG | 353 | In Stock |
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| 100MG | 530 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCY-09
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NoteResearch use only, not for human use.
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Brief DescriptionCY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor.
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DescriptionCY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity; suppresses NLRP3 inflammasome assembly and activation, shows remarkable therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes.
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In Vitro——
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In Vivo——
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SynonymsNLRP3 inhibitor CY-09
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PathwayNF-κB
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TargetNOD
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RecptorNLRP3|NLRP3?inhibitor
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number1073612-91-5
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Formula Weight423.424
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Molecular FormulaC19H12F3NO3S2
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Purity>98% (HPLC)
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SolubilityDMSO: 77 mg/mL (181.8 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(O)C1=CC=C(/C=C(SC(N2CC3=CC=CC(C(F)(F)F)=C3)=S)\C2=O)C=C1
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Chemical NameBenzoic acid, 4-[[4-oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jiang H, et al. J Exp Med. 2017 Nov 6;214(11):3219-3238.
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