CTPB( CTPB )

Catalog No. M15161 CAS No. 586976-24-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

CTPB
Note

Research use only, not for human use.
Brief Description

CTPB is an anacardic acid derivative, was reported as a selective activator of p300 (KAT3B) HAT activity but not PCAF (KAT2B).
Description

CTPB is an anacardic acid derivative, was reported as a selective activator of p300 (KAT3B) HAT activity but not PCAF (KAT2B), which enhanced HAT-dependent transcriptional activation; has no effect on histone deacetylase activity; promotes the survival and neurite growth of the SH-SY5Y cells, and also protects these cells from cell death induced by the neurotoxin 6-hydroxydopamine.
In Vitro

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In Vivo

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Synonyms

CTPB
Pathway

Chromatin/Epigenetic
Target

HAT
Recptor

HAT
Research Area

——
Indication

——

CAS Number

586976-24-1
Formula Weight

554.135
Molecular Formula

C31H43ClF3NO2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (112.79 mM)
SMILES

O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(CCCCCCCCCCCCCCC)C=CC=C2OCC
Chemical Name

N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl-benzamide

1. Balasubramanyam K, et al. J Biol Chem. 2003 May 23;278(21):19134-40. 2. Hegarty SV, et al. Neurotox Res. 2016 Oct;30(3):510-20.

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