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COX-2-IN-1
CAS No. 787623-48-7
COX-2-IN-1 ( —— )
Catalog No. M26018 CAS No. 787623-48-7
COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 264 | Get Quote |
|
| 5MG | 402 | Get Quote |
|
| 10MG | 593 | Get Quote |
|
| 25MG | 888 | Get Quote |
|
| 50MG | 1242 | Get Quote |
|
| 100MG | 1701 | Get Quote |
|
| 500MG | 3411 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCOX-2-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionCOX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).
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DescriptionCOX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).(In Vitro):COX-2-IN-1(compound 5f) is an inhibitor of COX-1 and COX-2 with IC50s of >100 and 3.9 μM, respectively.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorAlkyl-Chain
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Research Area——
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Indication——
Chemical Information
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CAS Number787623-48-7
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Formula Weight442.8
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Molecular FormulaC18H14ClF3N4O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESNS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2c(Cl)cccc12)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yang J, et al. Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders. J Med Chem. 2019 Oct 21.
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