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CMPD167
CAS No. 313994-79-5
CMPD167( CMPD 167 | MRK-1 )
Catalog No. M14012 CAS No. 313994-79-5
CMPD167 (MRK-1) is an orally acitve small molecule that binds to CCR5 to inhibit gp120 association.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCMPD167
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NoteResearch use only, not for human use.
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Brief DescriptionCMPD167 (MRK-1) is an orally acitve small molecule that binds to CCR5 to inhibit gp120 association.
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DescriptionCMPD167 (MRK-1) is an orally acitve small molecule that binds to CCR5 to inhibit gp120 association, inhibits different stages of the virus-cell attachment and entry process (CCR5-using virus SHIV-162P3, IC50<1 nM).
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In Vitro——
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In Vivo——
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SynonymsCMPD 167 | MRK-1
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number313994-79-5
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Formula Weight574.785
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Molecular FormulaC35H47FN4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCCN1C(=CC(=N1)CC2=CC=CC=C2)C3CCN(CC3)CC4CC(CC4C5=CC(=CC=C5)F)N(C)C(C(C)C)C(=O)O
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Chemical NameN-((1R,3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)cyclopentyl)-N-methyl-D-valine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Veazey RS, et al. Nature. 2005 Nov 3;438(7064):99-102.
2. Veazey RS, et al. Nat Med. 2005 Dec;11(12):1293-4.
3. Ketas TJ, et al. Virology. 2007 Aug 1;364(2):431-40.
4. Malcolm RK, et al. Antimicrob Agents Chemother. 2012 May;56(5):2251-8.
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