CMP8
CAS No. 851107-28-3
CMP8 ( —— )
Catalog No. M26655 CAS No. 851107-28-3
CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 468 | Get Quote |
|
10MG | 669 | Get Quote |
|
25MG | 1035 | Get Quote |
|
50MG | 1395 | Get Quote |
|
100MG | 1782 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameCMP8
-
NoteResearch use only, not for human use.
-
Brief DescriptionCMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD).
-
DescriptionCMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively.(In Vivo):CMP8 is dosed in male Balb-c mice (4 mg/kg, ip). In mammalian cells, the plasma concentration after 4 h is 1.5-fold its EC50. It has a Cmax of 0.5 μM after 30 min.
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetEstrogen Receptor/ERR
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number851107-28-3
-
Formula Weight528.1
-
Molecular FormulaC33H34ClNO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOc1ccc2C3=C(C(=O)CCC3(Cc3ccc(Cl)cc3)Cc2c1)c1ccc(OCCN2CCCCC2)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Wu WN, et al. Biotransformation of an antihypertensive arylalkylamine analogue in the rat. Xenobiotica. 1998 Oct;28(10):957-72.
molnova catalog
related products
-
Piceatannol 3'-O-glu...
Piceatannol 3'-O-glucoside increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung injury.
-
4,4-Iminodiphenol
4,4'-Iminodiphenol is an inactive estrogen receptor ligand with a diphenylamine backbone.
-
CMP8
CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD).