CKK-E12

CAS No. 1432494-65-9

CKK-E12( —— )

Catalog No. M36583 CAS No. 1432494-65-9

CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 128 Get Quote
5MG 188 Get Quote
10MG 312 Get Quote
25MG 609 Get Quote
50MG 975 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    CKK-E12
  • Note
    Research use only, not for human use.
  • Brief Description
    CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.
  • Description
    CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1432494-65-9
  • Formula Weight
    993.62
  • Molecular Formula
    C60H120N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (50.32 mM; Ultrasonic )
  • SMILES
    O=C1NC(C(=O)NC1CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dong Y, Love KT, Dorkin JR, et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates [published correction appears in Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5753].?Proc Natl Acad Sci U S A. 2014;111(11):3955-3960. ?
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