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CKK-E12

CAS No. 1432494-65-9

CKK-E12( —— )

Catalog No. M36583 CAS No. 1432494-65-9

CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CKK-E12
  • Note
    Research use only, not for human use.
  • Brief Description
    CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.
  • Description
    CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1432494-65-9
  • Formula Weight
    993.62
  • Molecular Formula
    C60H120N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (50.32 mM; Ultrasonic )
  • SMILES
    O=C1NC(C(=O)NC1CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dong Y, Love KT, Dorkin JR, et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates [published correction appears in Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5753].?Proc Natl Acad Sci U S A. 2014;111(11):3955-3960. ?
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