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CK-636
CAS No. 442632-72-6
CK-636( CK636 | CK 636 | CK-0944636 | CK0944636 | CK 0944636 )
Catalog No. M14507 CAS No. 442632-72-6
A small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 27 | In Stock |
|
| 10MG | 42 | In Stock |
|
| 25MG | 75 | In Stock |
|
| 50MG | 125 | In Stock |
|
| 100MG | 178 | In Stock |
|
| 500MG | 464 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCK-636
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex.
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DescriptionA small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex (SpArp2/3 complex, IC50 = 24 uM); inhibits formation of actin filament comet tails by Listeria and podosomes by monocytes.
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In Vitro——
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In Vivo——
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SynonymsCK636 | CK 636 | CK-0944636 | CK0944636 | CK 0944636
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetArp2/3 complex
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RecptorArp2/3complex(Bovine)|Arp2/3complex(Fissionyeast)|HumanArp2/3complex
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number442632-72-6
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Formula Weight284.376
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Molecular FormulaC16H16N2OS
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 49 mg/mL
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SMILESO=C(C1=CC=CS1)NCCC2=C(C)NC3=C2C=CC=C3
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Chemical Name2-Thiophenecarboxamide, N-[2-(2-methyl-1H-indol-3-yl)ethyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.
2. Zhou K, et al. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3820-9.
3. Weeks HP, et al. Anticancer Res. 2016 Mar;36(3):1135-42.
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