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CJ-13610
CAS No. 179420-17-8
CJ-13610( CJ13610 )
Catalog No. M12705 CAS No. 179420-17-8
CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 82 | Get Quote |
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| 10MG | 142 | Get Quote |
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| 25MG | 314 | Get Quote |
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| 50MG | 530 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCJ-13610
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NoteResearch use only, not for human use.
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Brief DescriptionCJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.
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DescriptionCJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM; demonstrates antihyperalgesic activity in inflammatory pain models including the acute carrageenan model and the chronic inflammatory model.Asthma Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsCJ13610
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PathwayImmunology/Inflammation
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TargetLipoxygenase
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RecptorLipoxygenase
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Research AreaInflammation/Immunology
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IndicationAsthma
Chemical Information
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CAS Number179420-17-8
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Formula Weight393.505
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Molecular FormulaC22H23N3O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (25.41 mM)
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SMILESO=C(C1(C2=CC=CC(SC3=CC=C(N4C=CN=C4C)C=C3)=C2)CCOCC1)N
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Chemical Nametetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fischer L, et al. Br J Pharmacol. 2004 Jul;142(5):861-8.
2. Cortes-Burgos LA, et al. Eur J Pharmacol. 2009 Sep 1;617(1-3):59-67.
3. von Knethen A, et al. Cell Signal. 2013 Dec;25(12):2762-8.
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