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CITCO
CAS No. 338404-52-7
CITCO ( —— )
Catalog No. M24287 CAS No. 338404-52-7
CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49?nM over pregnane X receptor (PXR), and no activity on other nuclear receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 51 | In Stock |
|
| 10MG | 82 | In Stock |
|
| 25MG | 149 | In Stock |
|
| 50MG | 239 | In Stock |
|
| 100MG | 357 | In Stock |
|
| 200MG | 537 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCITCO
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NoteResearch use only, not for human use.
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Brief DescriptionCITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49?nM over pregnane X receptor (PXR), and no activity on other nuclear receptors.
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DescriptionCITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49?nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorCAR;PXR
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Research Area——
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Indication——
Chemical Information
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CAS Number338404-52-7
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Formula Weight436.7
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Molecular FormulaC19H12Cl3N3OS
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Purity>98% (HPLC)
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SolubilityDMSO:soluble; H2O:insoluble
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SMILESClc(cc1)ccc1-c1c(/C=N/OCc(cc2)cc(Cl)c2Cl)n(ccs2)c2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chakraborty S, et al. Constitutive androstane receptor agonist CITCO inhibits growth and expansion of brain tumour stem cells. Br J Cancer. 2011 Feb 1;104(3):448-59.
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