CITCO
CAS No. 338404-52-7
CITCO ( —— )
Catalog No. M24287 CAS No. 338404-52-7
CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49?nM over pregnane X receptor (PXR), and no activity on other nuclear receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 51 | In Stock |
|
10MG | 82 | In Stock |
|
25MG | 149 | In Stock |
|
50MG | 239 | In Stock |
|
100MG | 357 | In Stock |
|
200MG | 537 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCITCO
-
NoteResearch use only, not for human use.
-
Brief DescriptionCITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49?nM over pregnane X receptor (PXR), and no activity on other nuclear receptors.
-
DescriptionCITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49?nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorCAR;PXR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number338404-52-7
-
Formula Weight436.7
-
Molecular FormulaC19H12Cl3N3OS
-
Purity>98% (HPLC)
-
SolubilityDMSO:soluble; H2O:insoluble
-
SMILESClc(cc1)ccc1-c1c(/C=N/OCc(cc2)cc(Cl)c2Cl)n(ccs2)c2n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Chakraborty S, et al. Constitutive androstane receptor agonist CITCO inhibits growth and expansion of brain tumour stem cells. Br J Cancer. 2011 Feb 1;104(3):448-59.
molnova catalog
related products
-
6,7-Dihydro-2H-cyclo...
6,7-Dihydro-2H-cyclopenta[c]pyridazin-3(5H)-one is an intermediate used to synthesize Pyridazine derivatives.
-
Vindesine sulfate
Vindesine sulfate is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.
-
Epiaschantin
(+)-Epiaschantin shows marginal cancer cell line inhibitory activities. It also has anti-platelet aggregation activity.