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CID-2011756
CAS No. 638156-11-3
CID-2011756( CID2011756 | CID 2011756 | CID-2011756 )
Catalog No. M15420 CAS No. 638156-11-3
CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate Y cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 123 | In Stock |
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| 50MG | 222 | In Stock |
|
| 100MG | 308 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCID-2011756
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NoteResearch use only, not for human use.
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Brief DescriptionCID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate Y cells.
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DescriptionCID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate Y cells.
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In VitroCID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC50 of 3.2 μM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser916 in LNCaP cancer cells with an EC50 of 10±0.7 μM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC50s of 0.6±0.1 μM and 0.7±0.2 μM for PKD2 and PKD3, respectively.
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In Vivo——
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SynonymsCID2011756 | CID 2011756 | CID-2011756
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PathwayApoptosis
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TargetSerine/threonin kinase
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RecptorPKD
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number638156-11-3
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Formula Weight396.87
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Molecular FormulaC22H21ClN2O3
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESO=C(C1=CC=C(C2=CC=CC(Cl)=C2)O1)NC3=CC=C(CN4CCOCC4)C=C3
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Chemical Name5-(3-chlorophenyl)-N-(4-(morpholinomethyl)phenyl)furan-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sharlow ER, et al. PLoS One. 2011;6(10):e25134.
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