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CG347B

CAS No. 1598426-03-9

CG347B( —— )

Catalog No. M23696 CAS No. 1598426-03-9

CG347B is a selective inhibitor of HDAC6.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 67 In Stock
5MG 110 In Stock
10MG 177 In Stock
25MG 318 In Stock
50MG 484 In Stock
100MG 672 In Stock
500MG 1404 In Stock
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Biological Information

  • Product Name
    CG347B
  • Note
    Research use only, not for human use.
  • Brief Description
    CG347B is a selective inhibitor of HDAC6.
  • Description
    CG347B is a selective inhibitor of HDAC6.
  • In Vitro
    HtrA1 is identified as a Cisplatin (HY-17394, CDDP) resistance-related gene in NSCLC cells, while CG347B shows no effect on normalized mRNA expression or protein level of HtrA1 in NCI-H460 (CDDP-resistant) cells.CG347B (200 nM; 48 h) slightly rescues the Foxp3 expression inhibition induced by IL-4 (15 ng/mL), indicating a potential inhibition happens on histone deacetylation in naive CD4+ T cells from WT B6 mice cultured under Treg-polarizing conditions (for 1-3 d).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1598426-03-9
  • Formula Weight
    283.33
  • Molecular Formula
    C16H17N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:249 mg/mL?(878.83 mM;?Need ultrasonic)
  • SMILES
    CCOC(c1cnc(NC2(CC2)c2ccccc2)nc1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Christopher M. YATES. Metalloenzyme inhibitor compounds. WO2018165520A1.
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