Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - HDAC - CG347B

CG347B

CAS No. 1598426-03-9

CG347B( —— )

Catalog No. M23696 CAS No. 1598426-03-9

CG347B is a selective inhibitor of HDAC6.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 67 In Stock
5MG 110 In Stock
10MG 177 In Stock
25MG 318 In Stock
50MG 484 In Stock
100MG 672 In Stock
500MG 1404 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    CG347B
  • Note
    Research use only, not for human use.
  • Brief Description
    CG347B is a selective inhibitor of HDAC6.
  • Description
    CG347B is a selective inhibitor of HDAC6.
  • In Vitro
    HtrA1 is identified as a Cisplatin (HY-17394, CDDP) resistance-related gene in NSCLC cells, while CG347B shows no effect on normalized mRNA expression or protein level of HtrA1 in NCI-H460 (CDDP-resistant) cells.CG347B (200 nM; 48 h) slightly rescues the Foxp3 expression inhibition induced by IL-4 (15 ng/mL), indicating a potential inhibition happens on histone deacetylation in naive CD4+ T cells from WT B6 mice cultured under Treg-polarizing conditions (for 1-3 d).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1598426-03-9
  • Formula Weight
    283.33
  • Molecular Formula
    C16H17N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:249 mg/mL?(878.83 mM;?Need ultrasonic)
  • SMILES
    CCOC(c1cnc(NC2(CC2)c2ccccc2)nc1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Christopher M. YATES. Metalloenzyme inhibitor compounds. WO2018165520A1.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • HDAC6 inhibitor NCT-...

    A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.

  • HDAC-IN-57

    HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 nM, and 107 nM, respectively.

  • Resminostat hydrochl...

    A potent inhibitor of HDAC1/3/6 with IC50s of 43-72 nM; induces hyperacetylation of histone H4 and apoptosis in MM cell lines (IC50=2.5-3 uM).

Sign In Join Free