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CEBPαinducer1

CAS No. 2374285-52-4

CEBPαinducer1( —— )

Catalog No. M24088 CAS No. 2374285-52-4

The compound is a potential inducer of myeloid differentiation via upregulation of C/EBP.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CEBPαinducer1
  • Note
    Research use only, not for human use.
  • Brief Description
    The compound is a potential inducer of myeloid differentiation via upregulation of C/EBP.
  • Description
    The compound is a potential inducer of myeloid differentiation via upregulation of C/EBP.
  • In Vitro
    C/EBPα inducer 1 (compound 78, 3 μM) causes myeloid differentiation differentiation.C/EBPα inducer 1 (compound 78) increases the expression of the neutrophil differentiation surface marker CD11b.C/EBPα inducer 1 (compound 78) induces the expression of the neutrophil differentiation surface marker CD11b and upregulation of CEBPA and its downstream targets.C/EBPα inducer 1 (compound 78) can upregulate G-CSF receptors, and render leukemic cells more sensitive to G-CSF stimulation.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2374285-52-4
  • Formula Weight
    377.33
  • Molecular Formula
    C20H12FN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1=CC=C(C=C1)N2C(=NC3=C(C2=O)C=C(C=C3)F)/C=C/C4=CC=C(O4)[N+](=O)[O-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sridhar R , Takei H , Syed R , et al. Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα[J]. Molecules, 2018, 23(8).
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