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CDK4-IN-1
CAS No. 1256963-02-6
CDK4-IN-1 ( LEE011 analog; CDK4-IN-1; CDK4IN-1; CDK4-IN1 )
Catalog No. M11055 CAS No. 1256963-02-6
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCDK4-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionCDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM.
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DescriptionCDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50=5.265 uM) respectively.
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SynonymsLEE011 analog; CDK4-IN-1; CDK4IN-1; CDK4-IN1
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK4; Cyclin D1
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Research Area——
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Indication——
Chemical Information
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CAS Number1256963-02-6
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Formula Weight440.97
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Molecular FormulaC22H29ClN8
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Purity>98%(HPLC)
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SolubilityDMSO: 10 mM
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SMILESCN(C1CCN(C2=CN=C(NC3=NC=CC(C4=C(C(C)C)NN=C4Cl)=N3)C=C2)CC1)C
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Chemical Name4-(3-Chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cho YS, et al. J Med Chem. 2010 Nov 25;53(22):7938-57.
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