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CD3254

CAS No. 196961-43-0

CD3254( —— )

Catalog No. M33310 CAS No. 196961-43-0

CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CD3254
  • Note
    Research use only, not for human use.
  • Brief Description
    CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.
  • Description
    CD3254 a potent and selective retinoid-X-receptor (RXR) agonist.
  • In Vitro
    Cell Viability AssayCell Line:zebrafish (Danio rerio) embryosConcentration:10, 20, 50, 100 μg/L Incubation Time:Result:The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Retinoid Receptor
  • Recptor
    Retinoid Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    196961-43-0
  • Formula Weight
    364.48
  • Molecular Formula
    C24H28O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (342.95 mM; Ultrasonic )
  • SMILES
    Cc1cc2c(cc1-c1cc(\C=C/C(O)=O)ccc1O)C(C)(C)CCC2(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nahoum V, et al. Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8.?
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