CCT-367766 ( CCT367766;CCT 367766 )

Catalog No. M13570 CAS No. 2229856-58-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

CCT-367766
Note

Research use only, not for human use.
Brief Description

CCT-367766 (CCT367766) is a novel heterobifunctional PROTAC that binds and degrades the putative transcription factor regulator Pirin in cells.
Description

CCT-367766 (CCT367766) is a novel heterobifunctional PROTAC that binds and degrades the putative transcription factor regulator Pirin in cells.
Synonyms

CCT367766;CCT 367766
Pathway

PROTACs
Target

PROTAC
Recptor

PROTAC
Research Area

——
Indication

——

CAS Number

2229856-58-8
Formula Weight

946.41
Molecular Formula

C49H48ClN7O11
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(C1=CC=C2N=C(CN3CCN(CCOCCOCCOC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)CC3)C=CC2=C1)NC7=CC(NC(C8=CC=C9OCCOC9=C8)=O)=CC=C7Cl
Chemical Name

N-(2-Chloro-5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)phenyl)-2-((4-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ethoxy)ethoxy)ethyl)piperazin-1-yl)methyl)quinoline-6-carboxamide

1. Chessum NEA, et al. J Med Chem. 2017 Dec 14. doi: 10.1021/acs.jmedchem.7b01406.

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