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CCCP

CAS No. 555-60-2

CCCP ( CCCP; Mesoxalonitrile 3-chlorophenylhydrazone )

Catalog No. M18806 CAS No. 555-60-2

CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP).

Purity : 98%

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
100MG	37	In Stock
200MG	52	In Stock
500MG	87	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

CCCP
Note

Research use only, not for human use.
Brief Description

CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP).
Description

m-Cl-CCP [555-60-2] is a protonophore (h+ ionophore) and uncoupler of oxidative phosphorylation in mitochondria, inhibiting secretion of hepatic lipase and partially inhibiting the ph gradient-activated cl- uptake and cl-/cl- exchange activities in brush-border membrane vesicles
Synonyms

CCCP; Mesoxalonitrile 3-chlorophenylhydrazone
Pathway

Others
Target

Other Targets
Recptor

TBK1; IFN-β
Research Area

——
Indication

——

Chemical Information

CAS Number

555-60-2
Formula Weight

204.62
Molecular Formula

C9H5ClN4
Purity

98%
Solubility

DMSO : ≥ 150 mg/mL; 733.07 mM
SMILES

Clc1cccc(NN=C(C#N)C#N)c1
Chemical Name

Carbonyl cyanide 3-chlorophenylhydrazone

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kwon D, et al. Biochem Biophys Res Commun. 2017 Aug 30. pii: S0006-291X(17)31704-7.

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