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CBB3001

CAS No. 1639358-50-1

CBB3001( CBB-3001 | CBB 3001 )

Catalog No. M12479 CAS No. 1639358-50-1

CBB3001 (CBB-3001) is a novel potent, selective histone demethylase LSD1 inhibitor with IC50 of 21.25 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CBB3001
  • Note
    Research use only, not for human use.
  • Brief Description
    CBB3001 (CBB-3001) is a novel potent, selective histone demethylase LSD1 inhibitor with IC50 of 21.25 uM.
  • Description
    CBB3001 (CBB-3001) is a novel potent, selective histone demethylase LSD1 inhibitor with IC50 of 21.25 uM; potently inhibits LSD1 activity both in vitro and in vivo; CBB3001 also selectively inhibits the growth of human ovarian teratocarcinoma PA-1 and mouse embryonic carcinoma F9 cells, caused the downregulation of pluripotent stem cell proteins SOX2 and OCT4, does not have significant inhibition on the growth of human colorectal carcinoma HCT116 cells or mouse fibroblast NIH3T3 cells that do not express these stem cell proteins.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CBB-3001 | CBB 3001
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    Histone Demethylase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1639358-50-1
  • Formula Weight
    349.427
  • Molecular Formula
    C19H27NO5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)OC(=O)NC1CC1C2=CC=C(C=C2)OC(=O)OC(C)(C)C
  • Chemical Name
    tert-butyl 2-(4-(tert-butoxycarbonyloxy)phenyl)cyclopropylcarbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hoang N, et al. Bioorg Med Chem. 2018 May 1;26(8):1523-1537.
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