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Home - Products - GPCR/G Protein - Prostaglandin Receptor - CAY10526

CAY10526

CAS No. 938069-71-7

CAY10526( CAY-10526 | CAY 10526 | BTH )

Catalog No. M27762 CAS No. 938069-71-7

CAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CAY10526
  • Note
    Research use only, not for human use.
  • Brief Description
    CAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
  • Description
    CAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.(In Vitro):CAY10526 dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 1.8 μM without any effect on COX-2 expression.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CAY-10526 | CAY 10526 | BTH
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    938069-71-7
  • Formula Weight
    311.15
  • Molecular Formula
    C12H7BrO3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 66.67 mg/mL (214.27 mM)
  • SMILES
    OC1OC(=O)C(Br)=C1c1cc2ccccc2s1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tadesse S, Zhu G, Mekonnen LB, Lenjisa JL, Yu M, Brown MP, Wang S. A novel series of N-(pyridin-2-yl)-4-(thiazol-5-yl)pyrimidin-2-amines as highly potent CDK4/6 inhibitors. Future Med Chem. 2017 Sep;9(13):1495-1506.
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