C527

CAS No. 192718-06-2

C527 ( —— )

Catalog No. M23878 CAS No. 192718-06-2

C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 42 In Stock
10MG 72 In Stock
25MG 155 In Stock
50MG 259 In Stock
100MG 435 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    C527
  • Note
    Research use only, not for human use.
  • Brief Description
    C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM).
  • Description
    C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM).
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    USP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    192718-06-2
  • Formula Weight
    293.3
  • Molecular Formula
    C17H8FNO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:< 1 mg/mL (insoluble or slightly soluble)
  • SMILES
    O=C(c1c2oc(-c(cc3)ccc3F)n1)c(cccc1)c1C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mistry H, et al. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec;12(12):2651-62.
molnova catalog
related products
  • NSC112200

    NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2.

  • USP10-IN-9

    USP10-IN-9 is a HBX19818 analog, selective USP10 inhibitor with IC50 similar to HBX19818.

  • IU1-248

    IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83?μM.