C29 ( TLR2-IN-C29; TLR2 IN C29; TLR2INC29; TLR2-inhibitor-C29 )

Catalog No. M17495 CAS No. 363600-92-4

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HPLC

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Product Name

C29
Note

Research use only, not for human use.
Brief Description

C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.
Description

TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.
Synonyms

TLR2-IN-C29; TLR2 IN C29; TLR2INC29; TLR2-inhibitor-C29
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

TLR2/1; TLR2/6
Research Area

Others-Field
Indication

——

CAS Number

363600-92-4
Formula Weight

285.3
Molecular Formula

C16H15NO4
Purity

98%
Solubility

DMSO : ≥ 30 mg/mL; 105.16 mM
SMILES

COc1cccc(\C=N\c2cccc(C(O)=O)c2C)c1O
Chemical Name

3-[[(2-Hydroxy-3-methoxyphenyl)methylene]amino]-2-methyl-benzoic acid

1. Pragnesh Mistry, J Immunol May 1, 2014, 192 (1 Supplement) 189.1.

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