Cart
sales@molnova.com
C004019
CAS No. 2417159-57-8
C004019( —— )
Catalog No. M36015 CAS No. 2417159-57-8
C004019 is a small molecule PROTAC capable of targeting tau for selective protein degradation from the cell, while recruiting tau and E3 ligase (Vhl) for selective enhancement of tau ubiquitination and proteollyzation. C004019 is a candidate for AD and related tau protein diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 400 | Get Quote |
|
| 5MG | 613 | Get Quote |
|
| 10MG | 896 | Get Quote |
|
| 25MG | 1270 | Get Quote |
|
| 50MG | 1730 | Get Quote |
|
| 100MG | 2277 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameC004019
-
NoteResearch use only, not for human use.
-
Brief DescriptionC004019 is a small molecule PROTAC capable of targeting tau for selective protein degradation from the cell, while recruiting tau and E3 ligase (Vhl) for selective enhancement of tau ubiquitination and proteollyzation. C004019 is a candidate for AD and related tau protein diseases.
-
DescriptionC004019 is a small-molecule PROTAC. C004019 simultaneously recruites tau and E3-ligase (Vhl) and thus selectively enhances ubiquitination and proteolysis of tau proteins. C004019 can be used for Alzheimer disease (AD) research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorPROTACs | Microtubule Associated
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2417159-57-8
-
Formula Weight1035.29
-
Molecular FormulaC49H70N12O9S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN(CC(NCCOCCOCCOCC(N[C@H](C(=O)N1[C@@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](O)C1)C(C)(C)C)=O)=O)(C)C4=NC(=NC(NCCC5=CC=CS5)=N4)N6CCN(C(C)=O)CCC6
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang W, et al. A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models. Theranostics. 2021 Mar 11;11(11):5279-5295. ?
molnova catalog
related products
-
LabMol-319
LabMol-319 is a potent Zika virus (ZIKV) NS5 RdRp inhibitor with antiviral activity for the study of ZIKV virus.
-
MDK1088
MDK-1088 (T.cruzi Inhibitor) is a Trypanosoma cruzi inhibitor.
-
Adjudin
Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.
