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Butyzamide
CAS No. 1110767-45-7
Butyzamide( —— )
Catalog No. M36057 CAS No. 1110767-45-7
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mouse pro B cell line Ba/F3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 433 | In Stock |
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| 5MG | 653 | In Stock |
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| 10MG | 948 | In Stock |
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| 25MG | 1362 | In Stock |
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| 50MG | 1831 | In Stock |
|
| 100MG | 2421 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameButyzamide
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NoteResearch use only, not for human use.
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Brief DescriptionButyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mouse pro B cell line Ba/F3.
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DescriptionButyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetJAK
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RecptorThrombopoietin Receptor | JAK
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Research Area——
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Indication——
Chemical Information
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CAS Number1110767-45-7
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Formula Weight591.55
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Molecular FormulaC29H32Cl2N2O5S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (169.05 mM; Ultrasonic )
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SMILESO(C)C1=C(C=CC=C1C(OCCC)C(C)(C)C)C=2N=C(NC(=O)C3=CC(Cl)=C(/C=C(/C(O)=O)\C)C(Cl)=C3)SC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nogami W, et al. The effect of a novel, small non-peptidyl molecule butyzamide on human thrombopoietin receptor and megakaryopoiesis. Haematologica. 2008 Oct;93(10):1495-504. ?
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