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Bufarenogin
CAS No. 17008-65-0
Bufarenogin( 3beta,12beta,14-Trihydroxy-11-oxo-5beta-bufa-20,22-dienolide )
Catalog No. M29106 CAS No. 17008-65-0
Bufarenogin is a bufadienolide isolated from parotoid gland secretions of the Cuban endemic toad Peltophryne fustiger. Bufarenogin shows anti-tumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 87 | In Stock |
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| 5MG | 170 | In Stock |
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| 10MG | 267 | In Stock |
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| 25MG | 462 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBufarenogin
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NoteResearch use only, not for human use.
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Brief DescriptionBufarenogin is a bufadienolide isolated from parotoid gland secretions of the Cuban endemic toad Peltophryne fustiger. Bufarenogin shows anti-tumor activity.
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DescriptionBufarenogin is a bufadienolide isolated from parotoid gland secretions of the Cuban endemic toad Peltophryne fustiger. Bufarenogin shows anti-tumor activity.(In Vitro):Bufarenogin caused cell death via apoptosis. Bufarenogin induced B-cell lymphoma 2-associated X protein (Bax)-dependent intrinsic apoptosis, as demonstrated by mitochondrial translocation of Bax and cytoplasm release of HCT116 wild-type cells and cytochrome C. Bufarenogin induced intrinsic apoptosis through the cooperation of Bax and adenine-nucleotide translocator and inhibited the metastasis and growth of orthotopical CRC cells.
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In VitroBufarenogin induced intrinsic apoptosis through the cooperation of Bax and adenine‐nucleotide translocator and inhibited the metastasis and growth of orthotopical CRC cells.
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In Vivo——
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Synonyms3beta,12beta,14-Trihydroxy-11-oxo-5beta-bufa-20,22-dienolide
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PathwayApoptosis
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TargetPERK
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RecptorERK
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Research Area——
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Indication——
Chemical Information
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CAS Number17008-65-0
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Formula Weight416.514
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Molecular FormulaC24H32O6
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@]12CC[C@]3([H])[C@]([H])(C(=O)[C@@H](O)[C@]4(C)[C@H](CC[C@]34O)c3ccc(=O)oc3)[C@@]1(C)CC[C@H](O)C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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