Boc-NH-PEG6-CH2COOH ( —— )

Catalog No. M26925 CAS No. 391684-36-9

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Boc-NH-PEG6-CH2COOH
Note

Research use only, not for human use.
Brief Description

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Antifection; Apoptosis; COX; Mycobacterium tuberculosis; NF-κB; PKA; Wnt/β-catenin
Research Area

——
Indication

——

Chemical Information

CAS Number

391684-36-9
Formula Weight

439.5
Molecular Formula

C19H37NO10
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCC(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhang C, et al. Gliotoxin Induces Cofilin Phosphorylation to Promote Actin Cytoskeleton Dynamics and Internalization of Aspergillus fumigatus Into Type II Human Pneumocyte Cells. Front Microbiol. 2019 Jun 18;10:1345.

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