Boc-C16-COOH

Research use only, not for human use.

Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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Others

Other Targets

CRF|inflammation

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843666-40-0

370.574

C22H42O4

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (269.85 mM)

CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years