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Bivalirudin
CAS No. 128270-60-0
Bivalirudin( Hirulog-1 | BG-8967 )
Catalog No. M20244 CAS No. 128270-60-0
Bivalirudin is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM respectively) enzymes that exhibit high fibrinogen-clotting activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 45 | In Stock |
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| 25MG | 60 | In Stock |
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| 50MG | 97 | In Stock |
|
| 100MG | 138 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBivalirudin
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NoteResearch use only, not for human use.
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Brief DescriptionBivalirudin is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM respectively) enzymes that exhibit high fibrinogen-clotting activities.
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DescriptionBivalirudin is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM respectively) enzymes that exhibit high fibrinogen-clotting activities.(In Vivo):Bivalirudin (2 mg/kg) delays both the time for appearance of first thrombus and the time for occlusion in P2Y12+/+ arteries, although neither prevented vessel occlusion.
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In Vitro——
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In VivoBivalirudin (2 mg/kg) delays both the time for appearance of first thrombus and the time for occlusion in P2Y12+/+?arteries, although neither prevented vessel occlusion.
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SynonymsHirulog-1 | BG-8967
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PathwayAutophagy
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TargetThrombin
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RecptorThrombin
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Research AreaCardiovascular Disease
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Indicationheparin-induced thrombocytopenia
Chemical Information
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CAS Number128270-60-0
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Formula Weight2180.29
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Molecular FormulaC98H138N24O33
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 10 mg/mL (4.59 mM)
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SMILESCC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Witting JI et al. Thrombin-specific inhibition by and slow cleavage of hirulog-1. Biochem J. 1992 May 1;283 ( Pt 3):737-43.
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