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Bis-Tos-PEG4

CAS No. 37860-51-8

Bis-Tos-PEG4( PROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate) )

Catalog No. M27007 CAS No. 37860-51-8

Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bis-Tos-PEG4
  • Note
    Research use only, not for human use.
  • Brief Description
    Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
  • Description
    Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    PROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Bcl-2| Caspase-3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    37860-51-8
  • Formula Weight
    502.59
  • Molecular Formula
    C22H30O9S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Golla Madhubabu, et al. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Toxicol In Vitro. 2014 Dec;28(8):1386-95.
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