Bimolane
CAS No. 74550-97-3
Bimolane ( AT-1727; AT1727; CCRIS 7574;Bimolane )
Catalog No. M19065 CAS No. 74550-97-3
Bimolane is a topoisomerase II inhibitor.
Purity : 98%
Size | Price / USD | Stock | Quantity |
2MG | 32 | In Stock |
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5MG | 47 | In Stock |
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10MG | 78 | In Stock |
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25MG | 187 | In Stock |
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50MG | 324 | In Stock |
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100MG | 443 | In Stock |
|
500MG | 1008 | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameBimolane
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NoteResearch use only, not for human use.
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Brief DescriptionBimolane is a topoisomerase II inhibitor.
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DescriptionBimolane is a topoisomerase II inhibitor. Bimolane has been widely used in China as an anti-neoplastic agent and for the treatment of psoriasis. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. The results of enzyme and DNA titration assays indicate that inhibition of topoisomerase II by bimolane occurred through interactions with DNA, similar to the mechanism seen with the epipodophyllotoxin-type inhibitors. These results provide evidence that bimolane is an inhibitor of topoisomerase II in vitro.
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SynonymsAT-1727; AT1727; CCRIS 7574;Bimolane
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PathwayOthers
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TargetOther Targets
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RecptorTopo II
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Research Area——
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Indication——
Chemical Information
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CAS Number74550-97-3
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Formula Weight452.51
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Molecular FormulaC20H32N6O6
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Purity98%
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Solubility——
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SMILESN1(C(=O)CN(CC1=O)CCN1CC(=O)N(C(=O)C1)CN1CCOCC1)CN1CCOCC1
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Chemical Name1-(morpholin-4-ylmethyl)-4-[2-[4-(morpholin-4-ylmethyl)-3,5-dioxopiperazin-1-yl]ethyl]piperazine-2,6-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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MFZ 10-7
MFZ 10-7 is anegative allosteric modulator of the mGluR5. In rats, MFZ 10-7 (i.p.) inhibits cocaine-induced reinstatement of drug-seeking behavior, cocaine-associated cue-induced cocaine-seeking behavior and intravenous cocaine self-administration.
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PLP 139-151
PLP (139-151) is amino acid residue residue 139 to 151 of myelin proteolipid protein (PLP). This peptide is used to induce relapsing-remitting (RR)-EAE model.
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NADH disodium salt h...
NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process NADH becomes oxidized to produce NAD+. A variety of enzymes use NADH plus H+ to reduce substrates generating NAD+ as well as the reduced product.