Bimolane

Research use only, not for human use.

Bimolane is a topoisomerase II inhibitor.

Bimolane is a topoisomerase II inhibitor. Bimolane has been widely used in China as an anti-neoplastic agent and for the treatment of psoriasis. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. The results of enzyme and DNA titration assays indicate that inhibition of topoisomerase II by bimolane occurred through interactions with DNA, similar to the mechanism seen with the epipodophyllotoxin-type inhibitors. These results provide evidence that bimolane is an inhibitor of topoisomerase II in vitro.

AT-1727; AT1727; CCRIS 7574;Bimolane

Others

Other Targets

Topo II

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74550-97-3

452.51

C20H32N6O6

98%

——

N1(C(=O)CN(CC1=O)CCN1CC(=O)N(C(=O)C1)CN1CCOCC1)CN1CCOCC1

1-(morpholin-4-ylmethyl)-4-[2-[4-(morpholin-4-ylmethyl)-3,5-dioxopiperazin-1-yl]ethyl]piperazine-2,6-dione

(-20℃)

With Ice Pack

≥ 2 years