Beta-Sitosterol

CAS No. 83-46-5

Beta-Sitosterol ( β-Sitosterol; 22,23-Dihydrostigmasterol )

Catalog No. M19156 CAS No. 83-46-5

β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 180 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Beta-Sitosterol
  • Note
    Research use only, not for human use.
  • Brief Description
    β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.
  • Description
    β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. β-Sitosterol, a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer. Although the exact mechanism of action of β-sitosterols is unknown, it may be related to cholesterol metabolism or anti-inflammatory effects (via interference with prostaglandin metabolism). β-Sitosterol induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells.
  • Synonyms
    β-Sitosterol; 22,23-Dihydrostigmasterol
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PPL
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    83-46-5
  • Formula Weight
    414.72
  • Molecular Formula
    C29H50O
  • Purity
    98%
  • Solubility
    DMSO : < 1 mg/mL; H2O : < 0.1 mg/mL
  • SMILES
    [C@@H]1(O)CC2=CC[C@@H]3[C@@H]([C@]2(CC1)C)CC[C@]1([C@H]3CC[C@@H]1[C@@H](CC[C@H](C(C)C)CC)C)C
  • Chemical Name
    (24R)-Ethylcholest-5-en-3beta-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wong HS, et al. PhytOthers Res. 2014 Jul;28(7):999-1006.
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