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Bendazac

CAS No. 20187-55-7

Bendazac( Bendazolic acid | AF-983 )

Catalog No. M21078 CAS No. 20187-55-7

Bendazac is an anticataract drug. It may act by preventing protein denaturation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bendazac
  • Note
    Research use only, not for human use.
  • Brief Description
    Bendazac is an anticataract drug. It may act by preventing protein denaturation.
  • Description
    Bendazac is an anticataract drug. It may act by preventing protein denaturation.(In Vitro):Bendazac is an anti-inflammatory agent endowed with protein antidenaturant properties effective for various inflammatory skin conditions. Bendazac has been shown to be a strong reacting substrate in a chemical oxidizing system, which mimics a physiological pathway of hydroxy radical generation.By using EPR spectroscopy of spin-labelled bovine serum albumin (BSA), Bendazac was shown to prevent the BSA denaturation induced by urea, heat and free radicals produced in the xanthine/xanthine oxidase system.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Bendazolic acid | AF-983
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    20187-55-7
  • Formula Weight
    282.29
  • Molecular Formula
    C16H14N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:56 mg/mL (198.38 mM)
  • SMILES
    O=C(O)COc1nn(Cc2ccccc2)c2ccccc12
  • Chemical Name
    2-((1-benzyl-1H-indazol-3-yl)oxy)acetic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Marques C Ramalho J S Pereira P et al. Bendazac decreases in vitro glycation of human lens crystallins. Decrease of in vitro protein glycation by bendazac[J]. Documenta Ophthalmologica 1995 90(4):395-404.
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