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Basiliximab
CAS No. 179045-86-4
Basiliximab( —— )
Catalog No. M36560 CAS No. 179045-86-4
Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody targeting the interleukin-2 receptor, demonstrating potent immunosuppressive activity for use in kidney transplantation studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 347 | Get Quote |
|
| 5MG | 708 | Get Quote |
|
| 10MG | 1121 | Get Quote |
|
| 25MG | 1638 | Get Quote |
|
| 50MG | 2190 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBasiliximab
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NoteResearch use only, not for human use.
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Brief DescriptionBasiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody targeting the interleukin-2 receptor, demonstrating potent immunosuppressive activity for use in kidney transplantation studies.
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DescriptionBasiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation.
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In VitroBasiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα.Basiliximab binds only to activated lymphocytes and macrophages/monocytes. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα.
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In VivoBasiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats.Animal Model:Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia Dosage:0.07 mg/rat Administration:IV infusion, once Result:Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorInterleukin
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Research Area——
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Indication——
Chemical Information
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CAS Number179045-86-4
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. McKeage K, et al. Basiliximab: a review of its use as induction therapy in renal transplantation. BioDrugs. 2010 Feb 1;24(1):55-76.?
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