Balsalazide( Balsalazide )

Catalog No. M19126 CAS No. 80573-04-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

Balsalazide
Note

Research use only, not for human use.
Brief Description

Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
Description

Balsalazide is an anti-inflammatory agent for treatment of Inflammatory Bowel Disease.
In Vitro

——
In Vivo

At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug.
Synonyms

Balsalazide
Pathway

Others
Target

Other Targets
Recptor

Lipoxygenase
Research Area

Inflammation/Immunology
Indication

——

CAS Number

80573-04-2
Formula Weight

357.32
Molecular Formula

C17H15N3O6
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 41 mg/mL; 114.74 mM
SMILES

OC(=O)CCNC(=O)c1ccc(cc1)\N=N\c1ccc(O)c(c1)C(O)=O
Chemical Name

(E)-5-[[[-4-(2-Carboxyethyl)aminocarbonyl]phenyl]azo]-2-hydroxybenzoic acid

1. Kruis W, et al. Gut, 2001. 49(6): p. 783-789.

Calculator

molnova catalog