Bacitracin ( Bacitracin )

Catalog No. M11703 CAS No. 1405-87-4

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Product Name

Bacitracin
Note

Research use only, not for human use.
Brief Description

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy.
Description

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.
Synonyms

Bacitracin
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

——

CAS Number

1405-87-4
Formula Weight

1422.73
Molecular Formula

C66H103N17O16S
Purity

>98%(HPLC)
Solubility

Water: 100 mg/mL (70.98 mM); DMSO: 100 mg/mL (70.98 mM)
SMILES

O=C(O)CC[C@@H](NC([C@@H](NC([C@H]1N=C([C@@H](N)[C@@H](C)CC)SC1)=O)CC(C)C)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]2C(N[C@H](CCCN)C(N[C@@H]([C@H](CC)C)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CN=CN4)C(N[C@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(NCCCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O
Chemical Name

(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

1.Toscano WA Jr, et al. Pharmacol Ther, 1982, 16(2), 199-210.

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