
BTTAA
CAS No. 1334179-85-9
BTTAA( —— )
Catalog No. M11329 CAS No. 1334179-85-9
A Cu(I)-stabilizing ligand that shows high activity in accelerating the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC); BTTAA-Cu(I) catalyst is the optimal choice for cell surface azide-alkyne ligation, mediates CuAAC and copper-free click chemistry.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 312 | Get Quote |
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10MG | 429 | Get Quote |
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25MG | 704 | Get Quote |
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50MG | 981 | Get Quote |
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100MG | 1323 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameBTTAA
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NoteResearch use only, not for human use.
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Brief DescriptionA Cu(I)-stabilizing ligand that shows high activity in accelerating the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC); BTTAA-Cu(I) catalyst is the optimal choice for cell surface azide-alkyne ligation, mediates CuAAC and copper-free click chemistry.
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DescriptionA Cu(I)-stabilizing ligand that shows high activity in accelerating the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC); BTTAA-Cu(I) catalyst is the optimal choice for cell surface azide-alkyne ligation, mediates CuAAC and copper-free click chemistry.
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In VitroBTTAAis a Cu(I)-stabilizing ligand. Using the Glu18AzF mutant of ubiquitin as a model system with C3-Tm3+ and C4-Tm3+, Cu-BTTAA performs significantly better as a catalyst than Cu-THPTA or Cu-TBTA. BTTAA proves to perform much better than THPTA (tris[(1-hydroxy-propyl-1H-1,2,3-triazol-4-yl)methyl]amine) or TBTA (tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine).
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADCs Linker/Click Chemistry
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number1334179-85-9
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Formula Weight430.5073
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Molecular FormulaC19H30N10O2
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Purity>98% (HPLC)
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SolubilityH2O: ≥ 34 mg/mL
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SMILESCC(C)(C)N1C=C(N=N1)CN(CC2=CN(N=N2)CC(=O)O)CC3=CN(N=N3)C(C)(C)C
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Chemical Name1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-dimethylethyl)-1H-1,2,3-triazol-4-yl]methyl]amino]methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Loh CT, et al. Bioconjug Chem. 2013 Feb 20;24(2):260-8.
2. Besanceney-Webler C, et al. Angew Chem Int Ed Engl. 2011 Aug 22;50(35):8051-6.
molnova catalog



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