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BTSA1
CAS No. 314761-14-3
BTSA1 ( —— )
Catalog No. M19903 CAS No. 314761-14-3
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 34 | In Stock |
|
| 5MG | 58 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 178 | In Stock |
|
| 50MG | 335 | In Stock |
|
| 100MG | 500 | In Stock |
|
| 500MG | 1098 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBTSA1
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NoteResearch use only not for human use.
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Brief DescriptionBTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
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DescriptionBTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
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Synonyms——
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBax
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Research Area——
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Indication——
Chemical Information
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CAS Number314761-14-3
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Formula Weight430.51
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Molecular FormulaC21H14N6OS2
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Purity>98% (HPLC)
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SolubilityDMSO: 65 mg/mL
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SMILESO=C1N(N=C(\C1=N/Nc1nccs1)c1ccccc1)c1nc(cs1)-c1ccccc1
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Chemical Name1H-Pyrazole-45-dione 3-phenyl-1-(4-phenyl-2-thiazolyl)- 4-[2-(2-thiazolyl)hydrazone]
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Reyna DE et al. Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia. Cancer Cell. 2017 Oct 9;32(4):490-505.e10.
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